most of the time I think its best to slowplay.. assuming its the end of a big tourney.
but it depends on what you mean by the nuts.
if you mean the nuts after the flop (ex flop 789 two spades you have 10 J hearts) where you are sure you have the best hand, but could be beated down the road, then you might want to bet.
but if you have the absolute best hand pretty much.. like 22 flop 22A then i think it should be slowplayed. If you check preflop then suddenly bet a lot on that flop, theyll probably think you have a 2 and fold